Mounjaro might make it easier to reduce weight, however it could possibly additionally have an effect on your bowel actions. Discover the connection between Mounjaro and constipation.
Mounjaro is likely one of the diabetes medicines that may hold blood sugar ranges in management and can assist individuals reduce weight. These two are necessary advantages of this injectable drug, however additionally they have potential unwanted side effects on the physique. Constipation is one such well being downside. Utilizing Mounjaro to handle sort diabetes or drop kilos can have an effect on your bowel actions. You might wrestle in the bathroom as it could possibly make your stool tougher. Fortunately there are some things you are able to do to save lots of constipation.
What’s Mounjaro?
Mounjaro is the model identify of Tilzepatide and is a medication in a pre-filled pen. This can be a blood glucose-lowering drug that’s typically prescribed in sufferers with sort 2 diabetes. “The drug works by activating two receptors referred to as GLP-1 (glucagon-like peptide-1) and two receptors referred to as GIP (gastric inhibitory polypeptide). It really works by stimulating the physique’s insulin manufacturing, if mandatory. It additionally limits the quantity of sugar produced by the liver, slows digestion and helps decrease blood sugar ranges.

The US Meals and Drug Administration recommends controlling blood glucose ranges in adults with sort 2 diabetes, reasonably than sort 2 diabetes or weight reduction. The beginning dose is 2.5 mg and must be subcutaneously injected as soon as per week into the stomach, thighs, or higher arms. After 4 weeks, the dosage might be elevated to five mg. The utmost dosage for this drug is 15 mg.
Mounjaro and constipation: Unwanted side effects of this diabetes remedy
In March 2025, the FDA shared that it obtained adversarial occasion studies that could possibly be associated to individuals utilizing tilzepatide at doses better than these authorised by the company. Based on the company, individuals skilled signs resembling vomiting, diarrhea, constipation and stomach ache. “Constipation is the anticipated adverse impact of Munjaro,” says Dr. Kharb.
That is how Mounjaro and constipation are linked:
- Diminished intestinal motion: This can make it easier to management your blood sugar and hold you full for a very long time, however diminished intestinal motion might contribute to constipation.
- I diminished my urge for food: There could also be a hyperlink between munjaro and constipation, as this drug can scale back urge for food. “In case you do not eat or drink an excessive amount of water, you may be much less consumption of fiber and physique fluids,” consultants say. Fiber is a nutrient that helps to let poop undergo collectively. However, correct liquid consumption is necessary because it helps to melt the stool.
- Modifications in fluid absorption: Whereas taking this remedy, stool water could also be absorbed, leading to a stiffer and tougher stool.
Mounjaro and Tuntipation: Learn how to get reduction?
Mounjaro and constipation could also be linked, however don’t fret. You possibly can take easy steps to take easy steps. It is advisable to give attention to easy way of life changes.
1. Preserve hydration
Be certain to have sufficient water to appease your stool and assist promote regular bowel actions. I’ve heard of people that emphasize ingesting 8-10 glasses of water on daily basis. Now, this wholesome behavior will assist soften your stool and recurrently defecate.
2. It is transferring
“Constipation might be prevented and handled by common bodily actions resembling strolling and swimming,” consultants say. Strolling helps digestion, notably after a meal, by stimulating intestinal exercise. This helps forestall slowing down intestinal motion.
3. Say sure to the fibers
Fiber is not only necessary for managing your weight. “By looking for a high-fiber weight loss plan, you may strengthen the majority of your stool and enhance intestine regularity,” says the skilled. Together with greens, they’re wealthy in fiber, so that they have kidney beans, chia seeds and prunes for constipation administration.
4. medication
There’s stool material softener that may assist save constipation. Some medicine embody magnesium citrate, sodium docusate, magnesium citrate, and polyethylene glycol. It’s a should to examine together with your physician about these medicines and their simply obtainable kinds.
What are the unwanted side effects of Mounjaro for digestion?
Aside from the connection between Mounjaro and constipation, it could possibly have an effect on your digestive well being in some ways. Different unwanted side effects of Mounjaro for digestion embody:
- nausea
- vomiting
- Indigestion
- diarrhea
“These are often extra intense when you begin the remedy or improve the dosage. Over time, your physique will grow to be extra adaptable. Due to this fact, resistance will develop and result in a lower within the severity of signs,” says Dr. Kharb.

Nevertheless, sure meals and drinks can exacerbate these points. “Oil-based and spicy meals are inclined to stimulate the digestive system, lengthen discomfort and trigger acid reflux disorder. Additionally, vented drinks contribute to fuel accumulation and acidity, worsening indigestion,” consultants say.
Mounjaro Lengthy-term unwanted side effects
There’s a hyperlink between Mounjaro and constipation, however taking medicines to handle sort 2 diabetes and reduce weight could cause unwanted side effects. The listing contains nausea and acute pancreatitis. It’s best to seek the advice of your physician in regards to the injection and dosage.
- It may have an effect on not solely muscle mass but additionally fats, which may result in muscle loss.
- Acute pancreatitis is a situation that happens when the pancreas is swollen and infected in a brief time frame, and in response to a examine revealed in Cureus, tilzepatide (Mounjaro) unwanted side effects are uncommon, however documented unwanted side effects.
- It could be gallstones.
Associated FAQs
What’s the finest fiber complement for Mounjaro?
Incorporating complete grains, fruits, greens and beans into your weight loss plan is the easiest way to assist digestive well being. These meals assist by growing your fiber consumption and selling common bowel actions. You may also go to a fiber complement like Metamucil, however seek the advice of your physician first.
Can I take laxatives with Mounjaro?
Laxatives can be utilized to alleviate constipation whereas taking Mounjaro, however ought to solely be taken after consulting your physician. Medical steerage ensures the suitable sort and dosage and prevents dependence and undesirable unwanted side effects.